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PROTAC TRIB2 degrader-1

TRIB2 Degrader

PROTAC TRIB2 degrader-1 selectively targets TRIB2 for degradation through the CRBN-dependent ubiquitin-proteasome pathway. This compound effectively inhibits cell proliferation and induces apoptosis, making it a valuable tool in cancer research. Its unique mechanism allows for targeted protein degradation, facilitating studies on TRIB2's role in various cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3100306-42-8
Applications	TRIB2 Degrader
Formula	C₄₅H₄₅FN₈O₆
Molecular Weight	812.89
SMILES	O=C(C1=NNC2=C1C=C(C3=CC=CN=C3F)C=C2)NC4=CC5=C(C=C4)CCN(C(CCCCCCCCCNC6=CC7=C(C(N(C(CC8)C(NC8=O)=O)C7=O)=O)C=C6)=O)C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.