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PROTAC USP7 Degrader-2

PROTAC USP7 Degrader

PROTAC USP7 Degrader-2 targets the ubiquitin-specific protease 7 (USP7) and functions as a selective degrader. Demonstrating a DC50 of 1.91 μM in TE-12 cells, this compound effectively inhibits the migration of upper gastrointestinal tract cancer cells, although its anti-proliferative activity is relatively modest. PROTAC USP7 Degrader-2 is valuable for research focused on metastatic upper gastrointestinal cancer, aiding in the exploration of therapeutic strategies targeting USP7.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3056612-67-7
Applications	PROTAC USP7 Degrader
Formula	C₄₂H₄₄Cl₂N₈O₆S
Molecular Weight	859.82
SMILES	CC1=C(C(C2=CC=NC3=C2SC(CN4C(C=CN(C4=O)CCCCCNC5=CC=CC6=C5C(N(C6=O)C7CCC(NC7=O)=O)=O)=O)=C3)=CC(Cl)=C1)NC8CCCNC8.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.