Fig. 1 · Structure
Documents & Downloads
Protectin D1
Neuroprotectin D1
Protectin D1 is a neuroprotectin synthesized by neuronal cells, belonging to a novel family of bioactive compounds derived from docosahexaenoic acid. It acts as a specialized pro-resolving mediator, demonstrating significant in vivo pro-resolving activities in various human disease models. Protectin D1 inhibits NALP3 inflammasomes and modulates the PI3K/AKT and HIF-1α signaling pathways, imparting anti-inflammatory effects by reducing reactive oxygen species (ROS) and the expression of pro-inflammatory cytokines IL-1β and IL-18. Its ability to enhance miRNA-210 expression and exert cardioprotective effects makes Protectin D1 a valuable compound for research focused on cardiovascular diseases and inflammatory disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 660430-03-5 |
| Applications | Neuroprotectin D1 |
| Formula | C22H32O4 |
| Molecular Weight | 360.49 |
| Synonyms | Neuroprotectin D1; NPD1 |
| SMILES | CC/C=C\C[C@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\C/C=C\CCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.