Fig. 1 · Structure
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Protein A (SPA)
immunoglobulin-binding protein
Protein A is an immunoglobulin-binding protein generated by Staphylococcus aureus, primarily targeting the Fc region of antibodies. It possesses significant biological activities, including the blockade of opsonophagocytosis, induction of B cell apoptosis, and formation of toxic immune complexes with IgG that lead to leukocyte necrosis. This reagent is valuable for research applications related to immune system disorders, including studies on virulence mechanisms and immune responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 308083-69-4 |
| Applications | immunoglobulin-binding protein |
| Synonyms | SPA |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.