Protein kinase D inhibitor 1

Catalog No.: A53965
PKD Inhibitor
Protein kinase D inhibitor 1 is a potent pan-PKD inhibitor that exhibits IC50 values between 17 to 35 nM. This compound selectively inhibits the phosphorylation of cortactin mediated by Protein kinase D, thereby influencing cellular processes related to cytoskeletal dynamics and signal transduction. It is valuable for research applications focused on studying PKD signaling pathways and their impact on various cellular functions.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionProtein kinase D inhibitor 1 is a potent pan-PKD inhibitor that exhibits IC50 values between 17 to 35 nM. This compound selectively inhibits the phosphorylation of cortactin mediated by Protein kinase D, thereby influencing cellular processes related to cytoskeletal dynamics and signal transduction. It is valuable for research applications focused on studying PKD signaling pathways and their impact on various cellular functions.
Product Information
Catalog NumA53965
FormulaC19H21N7
Molecular Weight347.42
CAS Number2489320-03-6
SMILESNC1=C2C(N(CC3CCNCC3)N=C2C4=CNC5=C4C=CC=C5)=NC=N1
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