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Protein kinase inhibitor 4

Protein Kinase Inhibitor

Protein Kinase Inhibitor 4 specifically targets TRK-A and ROS1, exhibiting IC50 values of 3.0 nM and 104 nM, respectively. This compound demonstrates significant inhibitory activity against these protein kinases, making it a valuable tool for studies focused on cancer research and signal transduction pathways. Its selective action allows for exploration of the roles of TRK-A and ROS1 in tumorigenesis and therapeutic resistance.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2278205-04-0
Applications	Protein Kinase Inhibitor
Formula	C₂₅H₂₄F₂N₆O₃S
Molecular Weight	526.56
SMILES	FC1=C(C=C(C=C1)F)[C@@H]2N(C3=NC4=C(C=NN4C=C3)NC(C5=CC=C(C=C5)NS(CC)(=O)=O)=O)CCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.