Fig. 1 · Structure

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Protosappanin A

Cat. No. A18956 CAS 102036-28-2

JAK2/STAT3 inhibitor

Protosappanin A is an immunosuppressive ingredient of the medicinal herb Caesalpinia sappan L.

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Biological Activity

Target & Activity

Target Activity Value
JAK2  
STAT3  

Cellular Effect

Cell Line Activity Value Description Reference
RAW264.7 IC50 12.5 μM Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method [PMID: 23127886]

Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 102036-28-2
Applications

JAK2/STAT3 inhibitor

Formula C15H12O5
Molecular Weight 272.25
Synonyms PTA
SMILES
O=C1CC2=CC(O)=C(O)C=C2C3=CC=C(O)C=C3OC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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