PRX-03140 is a selective 5-HT4 receptor agonist that effectively crosses the blood-brain barrier, exhibiting a Ki value of 110 nM against the rat brain 5-HT4 receptor. This compound enhances cortical levels of acetylcholine and histamine, making it a valuable tool for investigating cognitive function. PRX-03140 is particularly relevant for research applications related to Alzheimer’s disease, where modulation of neurotransmitter systems is critical.
PRX-03140 is a selective 5-HT4 receptor agonist that effectively crosses the blood-brain barrier, exhibiting a Ki value of 110 nM against the rat brain 5-HT4 receptor. This compound enhances cortical levels of acetylcholine and histamine, making it a valuable tool for investigating cognitive function. PRX-03140 is particularly relevant for research applications related to Alzheimer’s disease, where modulation of neurotransmitter systems is critical.
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