Fig. 1 · Structure
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PSB-0788
A2B Antagonist
PSB-0788 is a selective high-affinity antagonist of the A2B receptor, exhibiting an IC50 value of 3.64 nM and a Ki value of 0.393 nM. This compound is useful for investigating the role of A2B receptors in chronic inflammatory lung diseases, providing insights into potential therapeutic strategies for such conditions. Researchers can utilize PSB-0788 to explore the modulation of inflammatory responses mediated by A2B signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1027513-54-7 |
| Applications | A2B Antagonist |
| Formula | C25H27ClN6O4S |
| Molecular Weight | 543.04 |
| SMILES | O=C1NC2=C(C(N1CCC)=O)NC(C3=CC=C(S(=O)(N4CCN(CC4)CC5=CC=C(C=C5)Cl)=O)C=C3)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.