Fig. 1 · Structure
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Pseudomonas quinolone signal
Quorum-sensing Signaling Molecule
Pseudomonas quinolone signal (PQS) is a quorum-sensing signaling molecule derived from Pseudomonas aeruginosa, primarily functioning through the las quorum-sensing system. PQS is integral to regulating the expression of virulence factors, particularly lasB, and is involved in critical biological processes including iron acquisition, cytotoxicity, and outer-membrane vesicle biogenesis. Additionally, PQS modulates host immune responses, making it a valuable reagent for research into bacterial communication and pathogenicity mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 108985-27-9 |
| Applications | Quorum-sensing Signaling Molecule |
| Formula | C16H21NO2 |
| Molecular Weight | 259.35 |
| Synonyms | PQS |
| SMILES | O=C1C(O)=C(CCCCCCC)NC2=C1C=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.