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Pseudouridine 5'-triphosphate

Modified nucleoside

Pseudouridine 5'-triphosphate is a modified nucleoside that serves as a building block for RNA synthesis via polymerases. This compound enhances the stability and translational efficiency of RNA molecules and significantly reduces immunogenicity compared to traditional uridine-containing mRNAs. Due to these properties, Pseudouridine 5'-triphosphate is widely utilized in therapeutic RNA development, enabling more effective and durable mRNA applications in research and clinical settings.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1175-34-4
Applications	Modified nucleoside
Formula	C₉H₁₅N₂O₁₅P₃
Molecular Weight	484.14
Synonyms	Pseudo-UTP
SMILES	O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CNC2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.