Fig. 1 · Structure
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PST3.1a
N-acetylglucosamine glycosyltransferase Inhibitor
PST3.1a is a selective inhibitor of N-acetylglucosamine glycosyltransferase (MGAT5) with an IC50 of 2 μM. This compound effectively inhibits the invasiveness and proliferation of glioblastoma-initiating cells, making it a valuable reagent for research into tumor biology and potential therapeutic strategies in cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1096144-06-7 |
| Applications | N-acetylglucosamine glycosyltransferase Inhibitor |
| Formula | C32H33O6P |
| Molecular Weight | 544.57 |
| SMILES | O[C@@H]([P@@](O[C@@H]1COCC2=CC=CC=C2)(C3=CC=CC=C3)=O)[C@@H](OCC4=CC=CC=C4)[C@@H]1OCC5=CC=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.