Fig. 1 · Structure
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PTX-SS-COOH
Anti-cancer Agent
PTX-SS-COOH is a prodrug designed for targeted anti-cancer therapy, specifically acting as a redox-sensitive amphiphilic polymer. This compound displays significant anticancer efficacy through the formation of nanoparticles (BSA/Gel-SS-PTX/PTX-SS-COOH NPs), which are capable of effectively delivering payloads in the presence of high glutathione levels characteristic of solid tumors, such as breast cancer and melanoma. Researchers can utilize PTX-SS-COOH to enhance targeted delivery systems in cancer treatment, leveraging its unique responsiveness to the tumor microenvironment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1800077-28-4 |
| Applications | Anti-cancer Agent |
| Formula | C53H59NO17S2 |
| Molecular Weight | 1046.16 |
| SMILES | CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCSSCCC(O)=O)=O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C)C)O)OC(C7=CC=CC=C7)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.