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pTyr5 EGFR (988-993)

Phosphatase

[pTyr5] EGFR (988-993) is a peptide derived from the autophosphorylation site at Tyr992 of the epidermal growth factor receptor (EGFR 988-993). This reagent is valuable for studying the regulation of EGFR signaling pathways, particularly in the context of phosphatase activity. It is frequently employed in research applications involving the interaction with catalytically inactive protein-tyrosine phosphatase 1B (PTP1B), providing insights into cellular signaling mechanisms and the role of phosphorylation in receptor activation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	159453-08-4
Applications	Phosphatase
Formula	C₃₁H₄₅N₆O₁₇P
Molecular Weight	804.69
SMILES	[C@@H](CC1=CC=C(OP(=O)(O)O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C(N[C@@H](CC(C)C)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.