Fig. 1 · Structure
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pUL89 Endonuclease-IN-2
HCMV pUL89 Endonuclease Inhibitor
pUL89 Endonuclease-IN-2 is a selective inhibitor of the human cytomegalovirus (HCMV) pUL89 endonuclease, exhibiting an IC50 value of 3.0 μM. This compound demonstrates significant antiviral activity, making it a valuable tool for research focused on HCMV pathogenesis and therapeutic intervention strategies. Its inhibition of pUL89 endonuclease plays a critical role in understanding the viral life cycle and developing antiviral agents against HCMV.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 519021-48-8 |
| Applications | HCMV pUL89 Endonuclease Inhibitor |
| Formula | C17H12F3N3O3S |
| Molecular Weight | 395.36 |
| SMILES | OC1=C(C(NCC2=CC=C(C(F)(F)F)C=C2)=O)N=C(C3=CC=CS3)N=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.