Fig. 1 · Structure
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Purine nucleoside phosphorylase, Microorganism
Purine Metabolizing Enzyme
Purine Nucleoside Phosphorylase (PNP) is a purine metabolizing enzyme essential for the purine salvage pathway. It catalyzes the cleavage of glycosidic bonds between ribose or deoxyribonucleosides and inorganic orthophosphate, leading to the formation of purine bases and ribose (or deoxyribose)-1-phosphate. This enzyme plays a critical role in maintaining T cell function; its deficiency can lead to impaired immune responses. PNP is valuable for research in immunology, metabolism, and genetic disorders related to purine metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9030-21-1 |
| Applications | Purine Metabolizing Enzyme |
| Synonyms | PNP |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.