Search by product name, CAS, target or catalog number. Press Down Arrow to reach product suggestions, Tab to move between links, and Escape to close suggestions.
CDK inhibitor
In Stock
Tell us your preferred amount per vial. We’ll confirm the options.
| Target | Activity | Value |
|---|---|---|
| Cdc2/CyclinB | 4 nM | |
| CDK2/CyclinE | 35 nM | |
| CDK2/CyclinA | 70 nM | |
| CDK4/CyclinD1 | 850 nM |
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| HT-29 | IC50 | > 100 μM | Cytotoxicity against human HT-29 cells by MTT assay | [PMID: 20804197] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 212844-53-6 |
| Applications | CDK inhibitor |
| Formula | C19H25ClN6O |
| Molecular Weight | 388.89 |
| Synonyms | NG-60 |
| SMILES | CC(C)N1C2=NC(N[C@H](C(C)C)CO)=NC(NC3=CC(Cl)=CC=C3)=C2N=C1 |
| Solvent | Reported Solubility |
|---|---|
| DMSO | Warmed: 53 mg/mL (136.28 mM) |
| Water | Insoluble |
| Ethanol | Warmed: 11 mg/mL (28.28 mM) |
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
