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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15517 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 388.89 |
| Formula | C19H25ClN6O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 212844-53-6 |
| Synonyms | NG-60 |
| SMILES code | CC(C)?N1C2=NC(N[[email protected]]?(C(C)?C)?CO)?=NC(NC3=CC(Cl)?=CC=C3)?=C2N=C1 |
| Chemical Name | 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine |
Description |
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. | ||||||||||
Targets |
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||||||||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.71 mL | 128.57 mL | 257.14mL |
| 0.5 mM | 5.14 mL | 25.71 mL | 51.43 mL |
| 1 mM | 2.57 mL | 12.86 mL | 25.71 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
*The above data is based on the productmolecular weight 388.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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