Signaling Pathway
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| Discription | Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. | ||
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| Targets |
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| Catalog Num | A15517 |
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| Formula | C19H25ClN6O |
| Molecular Weight | 388.89 |
| CAS Number | 212844-53-6 |
| SMILES | CC(C)N1C2=NC(N[C@H](C(C)C)CO)=NC(NC3=CC(Cl)=CC=C3)=C2N=C1 |
| Synonyms | NG-60 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Warmed: 53 mg/mL (136.28 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 11 mg/mL (28.28 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.71 mL | 128.57 mL | 257.14 mL |
| 0.5 mM | 5.14 mL | 25.71 mL | 51.43 mL |
| 1 mM | 2.57 mL | 12.86 mL | 25.71 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
