PX 12

Catalog No.: A13831

Trx-1 inhibitor

PX 12

PX 12 Chemical Structure

CAS NO. 141400-58-0

PX 12 inhibits hypoxia-induced HIF-1a transcriptional activity (IC50 11 nM) and proliferation of HT29 and MCF-7 tumor cells (IC50 1.9 and 0.9 uM, respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $85.00

Special Price $76.50

25 mg

Regular Price: $160.00

Special Price $144.00

50 mg

Regular Price: $300.00

Special Price $270.00

100 mg

Regular Price: $500.00

Special Price $450.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PX 12 inhibits hypoxia-induced HIF-1a transcriptional activity (IC50 11 nM) and proliferation of HT29 and MCF-7 tumor cells (IC50 1.9 and 0.9 uM, respectively).
Targets
Trx-1
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 53.1 mL 265.52 mL 531.04 mL
0.5 mM 10.62 mL 53.1 mL 106.21 mL
1 mM 5.31 mL 26.55 mL 53.1 mL
5 mM 1.06 mL 5.31 mL 10.62 mL

*The above data is based on the productmolecular weight 188.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13831
Actions Inhibitor
M. Wt 188.31
Formula C7H12N2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 141400-58-0
Synonyms IV-2, PX-12, PX12
SMILES CCC(C)SSC1=NC=CN1

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