PX-478 HCl

Catalog No.: A14319

HIF-1alpha inhibitor

PX-478 HCl

PX-478 HCl Chemical Structure

CAS NO. 685898-44-6

PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $140.00

Special Price $112.00

25 mg

Regular Price: $250.00

Special Price $200.00

50 mg

Regular Price: $350.00

Special Price $280.00

10mM * 1mL in DMSO
$85.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potential antineoplastic activity. PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity.
Targets
HIF-1α
In vitro DMSO 78 mg/mL (197.9 mM)
Water 78 mg/mL (197.9 mM)
Ethanol 78 mg/mL (197.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.37 mL 126.86 mL 253.73 mL
0.5 mM 5.07 mL 25.37 mL 50.75 mL
1 mM 2.54 mL 12.69 mL 25.37 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14319
Actions Inhibitor
M. Wt 394.12
Formula C13H20Cl4N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 685898-44-6
Synonyms 0
SMILES C1=CC(=CC=C1C[[email protected]@H](C(=O)O)N)[N+](CCCl)(CCCl)[O-].Cl.Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy PX-478 HCl | PX-478 HCl Supplier | purchase PX-478 HCl | PX-478 HCl cost | PX-478 HCl manufacturer | order PX-478 HCl | PX-478 HCl distributor | buy 685898-44-6| 685898-44-6 Supplier | purchase 685898-44-6 | 685898-44-6 cost | 685898-44-6 manufacturer | order 685898-44-6 | 685898-44-6 distributor
Rewards