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PXR Ligand 2

PXR Ligand

PXR Ligand 2 (Compound 55) is a potent ligand for the pregnane X receptor (PXR), a nuclear receptor involved in the regulation of drug metabolism and detoxification pathways. This compound facilitates the targeted degradation of SMARCA2 and SMARCA4 through PROTAC technology, making it a valuable tool for investigating chromatin remodeling and cancer biology. Its application in targeted protein degradation studies positions PXR Ligand 2 as a crucial reagent for research in molecular biology and pharmacology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3059971-00-2
Applications	PXR Ligand
Formula	C₃₃H₃₈N₄O₇
Molecular Weight	602.68
SMILES	O=C(C1=CC=C(C(NC(C2=C(N(N=N2)C3=CC(OC)=C(C=C3OC)OCC4=CC=CC=C4)C)=O)=C1)O[C@@H](CC)CCC)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.