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PXT-012253

PET Ligand

PXT-012253 is a positron emission tomography (PET) ligand targeting the metabotropic glutamate receptor 4 (mGluR4) by binding to an allosteric site. This compound demonstrates key biological activity in imaging studies and is particularly relevant for research into Parkinson's disease and levodopa-induced dyskinesia. PXT-012253 facilitates the exploration of mGluR4 modulation in these pathologies, enhancing understanding of receptor dynamics and pharmacological interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1835647-08-9
Applications	PET Ligand
Formula	C₁₃H₁₁ClN₂OS
Molecular Weight	278.76
SMILES	O=C(C1=NC=CC=C1)NC2=CC=C(C(SC)=C2)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.