Fig. 1 · Structure
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Pyridazinediones-derivative-1
Drug Derivative
Pyridazinediones-derivative-1 is a drug derivative with promising potential in the treatment of neurodegenerative disorders. It exhibits an ED50 of 2.1 μM for the inhibition of glutamate-induced contractions in isolated guinea pig ileum, indicating its ability to modulate excitatory neurotransmission. This compound may be valuable for research applications focused on neuronal protection and the exploration of therapeutic interventions for neurological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 147493-44-5 |
| Applications | Drug Derivative |
| Formula | C11H6ClN3O3 |
| Molecular Weight | 263.64 |
| SMILES | O=C1NNC(C2=NC3=CC(Cl)=CC=C3C(O)=C21)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.