Fig. 1 · Structure

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Pyroglutamylleucine

Dysbiosis Modulator

Pyroglutamylleucine (pGlu-Leu) functions as a dysbiosis modulator, exerting its effects through the enhancement of host antimicrobial peptides, particularly Rattusin. This orally active peptide is found in specific food protein hydrolysates and traditional Japanese fermented foods. By promoting the production of antimicrobial peptides, Pyroglutamylleucine plays a crucial role in restoring microbial balance, making it a valuable compound for research into gut health and dysbiosis-related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 21282-11-1
Applications Dysbiosis Modulator
Formula C11H18N2O4
Molecular Weight 242.27
Synonyms pGlu-Leu; pyroGlu-Leu
SMILES
CC(C)C[C@@H](C(O)=O)NC([C@@H]1CCC(N1)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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