Pyrotinib dimaleate

Catalog No.: A21756

EGFR/HER2 dual inhibitor

Pyrotinib dimaleate

Pyrotinib dimaleate Chemical Structure

CAS NO. 1397922-61-0

Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 s of 13 and 38 nM, respectively.

Availability: In stock

Package Price Qty
1 mg
$205.00
5 mg
$616.00
10 mg
$1,049.00
50 mg
$3,146.00
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Biological Activity

Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 s of 13 and 38 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.27 mL 61.33 mL 122.67 mL
0.5 mM 2.45 mL 12.27 mL 24.53 mL
1 mM 1.23 mL 6.13 mL 12.27 mL
5 mM 0.25 mL 1.23 mL 2.45 mL

*The above data is based on the productmolecular weight 815.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21756
Actions Inhibitor
M. Wt 815.22
Formula C40H39ClN6O11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1397922-61-0
Synonyms SHR-1258 dimaleate, SHR1258, SHR 1258
SMILES O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[[email protected]@H]5N(C)CCC5.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

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