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$0.00 Biological Activity
Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 s of 13 and 38 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.27 mL | 61.33 mL | 122.67 mL |
| 0.5 mM | 2.45 mL | 12.27 mL | 24.53 mL |
| 1 mM | 1.23 mL | 6.13 mL | 12.27 mL |
| 5 mM | 0.25 mL | 1.23 mL | 2.45 mL |
*The above data is based on the productmolecular weight 815.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21756 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 815.22 |
| Formula | C40H39ClN6O11 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1397922-61-0 |
| Synonyms | SHR-1258 dimaleate, SHR1258, SHR 1258 |
| SMILES | O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[[email protected]@H]5N(C)CCC5.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O |
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