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Pyrrocidine B

Secondary Metabolite

Pyrrocidine B is a microbial alkaloid identified as a secondary metabolite from the endophytic fungus Neonectria ramulariae Wollenw KS-246. It exhibits notable cytotoxic effects against leukemia cells, with an IC50 value of 4.6 μM for HL60 cell lines. Additionally, Pyrrocidine B displays weak inhibitory activity towards Prolyl oligopeptidase (POP), making it a potential candidate for research in cancer biology and enzymatic regulation studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	428439-25-2
Applications	Secondary Metabolite
Formula	C₃₁H₃₉NO₄
Molecular Weight	489.65
SMILES	C[C@]1(C[C@@H]2C)[C@](C(C)=C3)([H])[C@]([C@](C([C@](C(N4)=O)([H])C[C@@]4(C5)O)=O)([H])[C@@H]3C=C)([H])[C@@](OC6=CC=C5C=C6)([H])[C@]1([H])[C@H](C2)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.