Fig. 1 · Structure
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Pyrrolidine linoleamide
Derivative of Linoleic Acid Amide
Pyrrolidine linoleamide is a derivative of linoleic acid amide that exhibits notable anticancer activity. It demonstrates significant antiproliferative effects against various cancer cell lines, with IC50 values of 12.0 μg/mL against U251, 27.5 μg/mL against MCF-7, 7.7 μg/mL against NCI-ADR/RES, 21.9 μg/mL against 786-0, 36.6 μg/mL against NCI-H460, 32.6 μg/mL against PC-3, and 33.9 μg/mL against OVCAR-3. This compound is of significant interest for research targeting cancer therapeutics due to its differential activity against a range of models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3140-51-0 |
| Applications | Derivative of Linoleic Acid Amide |
| Formula | C22H39NO |
| Molecular Weight | 333.55 |
| SMILES | CCCCC/C=C\C/C=C\CCCCCCCC(N1CCCC1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.