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Pyrrolidone carboxylic acid

Hydrating Agent

Pyrrolidone carboxylic acid (PCA) is a hydrating agent primarily found in the natural moisturizing factor (NMF) of the skin. It plays a crucial role in maintaining skin hydration and serves as an important cutaneous biomarker for assessing skin barrier function and overall health. PCA is applicable in dermatological research and cosmetic formulations aimed at improving skin moisture retention.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	115621-24-4
Applications	Hydrating Agent
Formula	C₅H₇NO₃
Molecular Weight	129.11
Synonyms	PCA
SMILES	O=C(N1C(CCC1)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.