Fig. 1 · Structure
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Pyruvate Carboxylase-IN-1
Pyruvate Carboxylase Inhibitor
Pyruvate Carboxylase-IN-1 is a potent inhibitor of pyruvate carboxylase, an enzyme critical for gluconeogenesis and anaplerotic metabolism. With IC50 values of 0.204 μM in cell lysates and 0.104 μM in live cells, this compound demonstrates significant antiproliferative activity. Pyruvate Carboxylase-IN-1 is valuable for research applications focused on metabolic regulation, cancer biology, and therapeutic strategies targeting metabolic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 70205-50-4 |
| Applications | Pyruvate Carboxylase Inhibitor |
| Formula | C15H14O3 |
| Molecular Weight | 242.27 |
| SMILES | OC(C=C(OC)C=C1CC2)=C1C3=C2C=CC=C3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.