Fig. 1 · Structure
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Quassin
Anti-plasmodial Agent
Quassin is a bioactive triterpenoid derived from the stem bark of Quassia amara, primarily known for its anti-plasmodial properties. It exhibits significant inhibitory activity against Plasmodium falciparum, with an IC50 value of 0.15 μM. In addition to its anti-plasmodial effects, Quassin also demonstrates reversible antifertility and anti-estrogenic activities, making it a versatile compound for various biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 76-78-8 |
| Applications | Anti-plasmodial Agent |
| Formula | C22H28O6 |
| Molecular Weight | 388.45 |
| Synonyms | Nigakilactone D |
| SMILES | C[C@@H]([C@@]1(C[C@]2(OC(C[C@]([C@]2([C@]3([C@@]41C)[H])C)(C(C)=C(OC)C3=O)[H])=O)[H])[H])C=C(OC)C4=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.