Fig. 1 · Structure
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Quercetin 3-gentiobioside
Aromatase Inhibitor
Quercetin 3-gentiobioside is a flavonoid that serves as a potent aromatase inhibitor, exhibiting a Ki value of 46.77 nM. In addition to its aromatase inhibiting properties, it also demonstrates inhibitory activity against aldose reductase and the formation of advanced glycation end products, with IC50 values of 10.60 μM and 109.46 μM, respectively. Furthermore, Quercetin 3-gentiobioside has been shown to inhibit the proliferation of cancerous cells and fibroblast-like synoviocytes, making it a valuable compound in cancer research, particularly in the context of lung carcinoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 7431-83-6 |
| Applications | Aromatase Inhibitor |
| Formula | C27H30O17 |
| Molecular Weight | 626.52 |
| SMILES | O=C1C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)=C(C4=CC(O)=C(O)C=C4)OC5=CC(O)=CC(O)=C51 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.