Fig. 1 · Structure

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Quetiapine sulfone

Quetiapine Metabolite

Quetiapine sulfone is a primary metabolite of Quetiapine, acting predominantly as a serotonin (5-HT) receptor agonist and a dopamine receptor antagonist. This compound is essential for studying the pharmacokinetics and efficacy of Quetiapine in various neurological disorders, including schizophrenia and bipolar disorder. Its role in modulating neurotransmitter systems makes it a valuable reagent for researchers exploring antipsychotic mechanisms and drug metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 329216-65-1
Applications Quetiapine Metabolite
Formula C21H25N3O4S
Molecular Weight 415.51
SMILES
O=S1(C2=CC=CC=C2N=C(N3CCN(CCOCCO)CC3)C4=CC=CC=C41)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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