Fig. 1 · Structure
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Quoromycin
SmcR Inhibitor
Quoromycin is a selective inhibitor of SmcR, demonstrating a Kd of 0.697 μM for Vibrio vulnificus SmcR. By binding directly to SmcR, Quoromycin diminishes its affinity for DNA, effectively disrupting the quorum sensing signaling pathway. This compound is valuable for investigating the mechanisms underlying Vibrio vulnificus infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 205514-29-0 |
| Applications | SmcR Inhibitor |
| Formula | C12H8N2O2S |
| Molecular Weight | 244.27 |
| SMILES | N#CC1=CN=C(C=C1)S(=O)(=O)C=2C=CC=CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.