Fig. 1 · Structure

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R-116010

RA Metabolism Inhibitor

R-116010 is a selective inhibitor of retinoic acid (RA) metabolism, primarily targeting the hydroxylase CYP26. This compound is known to enhance the anti-tumor effects of retinoic acid, making it valuable for cancer research. Additionally, R-116010 has potential applications in studying metabolic and neurological disorders, including neuroblastoma.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 355860-40-1
Applications RA Metabolism Inhibitor
Formula C21H23N5S
Molecular Weight 377.51
SMILES
C[C@H](N(C)C)[C@H](C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4C=CN=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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