Fig. 1 · Structure
Documents & Downloads
(R)-3-Hydroxy Midostaurin
Kinases Inhibitor
(R)-3-Hydroxy Midostaurin is a potent kinase inhibitor, serving as a significant metabolite of midostaurin (PKC412) formed through CYP3A4-mediated metabolism. This compound exhibits promising biological activity, particularly in the context of acute myeloid leukemia (AML) research. Its inhibition of kinase activity can provide valuable insights into the molecular mechanisms underlying AML and may aid in developing targeted therapeutic strategies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 155848-20-7 |
| Applications | Kinases Inhibitor |
| Formula | C35H30N4O5 |
| Molecular Weight | 586.64 |
| Synonyms | (R)-CGP52421 |
| SMILES | O[C@H]1NC(C2=C1C(C3=C4C=CC=C3)=C5N4[C@]6(O[C@@H](N7C5=C2C8=C7C=CC=C8)C[C@H]([C@H]6OC)N(C(C9=CC=CC=C9)=O)C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.