Fig. 1 · Structure
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R(+)-8-OH-DPAT hydrobromide
5-HT1A Agonist
R(+)-8-OH-DPAT hydrobromide is a selective agonist of the 5-HT1A receptor, known for its significant efficacy in modulating serotonergic signaling. This compound enhances dopamine release in the medial prefrontal cortex, thereby providing valuable insights into the relationship between serotonin and dopamine neurotransmission. R(+)-8-OH-DPAT is widely utilized in research focused on neuropharmacology and behavioral studies related to mood disorders and cognition.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 78095-19-9 |
| Applications | 5-HT1A Agonist |
| Formula | C16H26BrNO |
| Molecular Weight | 328.29 |
| Synonyms | (R)-8-Hydroxy-2-dipropylaminotetralin hydrobromide |
| SMILES | OC1=C2C[C@H](N(CCC)CCC)CCC2=CC=C1.Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.