Fig. 1 · Structure
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(R)-(+)-Aminoglutethimide
Aromatase Inhibitor
(R)-(+)-Aminoglutethimide is a potent, orally active aromatase inhibitor that effectively reduces estrogen synthesis. This compound has shown significant potential in breast cancer research, providing insights into hormonal regulation and therapeutic strategies for estrogen-dependent tumors. Its mechanism of action makes it a valuable tool for studying the role of estrogens in cancer progression and treatment resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 55511-44-9 |
| Applications | Aromatase Inhibitor |
| Formula | C13H16N2O2 |
| Molecular Weight | 232.28 |
| Synonyms | d-Aminoglutethimide |
| SMILES | O=C([C@@](CC)(C1=CC=C(N)C=C1)CC2)NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.