Fig. 1 · Structure
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(R)-AMPA
iGluR
(R)-AMPA is a selective modulator of ionotropic glutamate receptors (iGluR), primarily acting on AMPA receptors. This compound serves to inhibit the release of excitatory amino acids from neurons, displaying inactivity in enhancing the release of [3H]D-aspartate during electrical stimulation. Additionally, (R)-AMPA’s biological activity can be effectively reversed by both competitive and noncompetitive antagonists targeting AMPA receptors, making it a valuable tool for research into neurotransmitter release and synaptic transmission.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 83654-13-1 |
| Applications | iGluR |
| Formula | C7H10N2O4 |
| Molecular Weight | 186.17 |
| SMILES | O=C1C(C[C@@H](N)C(O)=O)=C(C)ON1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.