(R)-AZ8838 is a competitive antagonist of the human PAR2 (protease-activated receptor 2) with a pKi value of 5.2. This compound demonstrates anti-inflammatory effects, evidenced in a rat model of PAR2 agonist-induced paw edema. It is valuable for research applications focusing on inflammation, pain modulation, and receptor signaling pathways.
(R)-AZ8838 is a competitive antagonist of the human PAR2 (protease-activated receptor 2) with a pKi value of 5.2. This compound demonstrates anti-inflammatory effects, evidenced in a rat model of PAR2 agonist-induced paw edema. It is valuable for research applications focusing on inflammation, pain modulation, and receptor signaling pathways.
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