Fig. 1 · Structure
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(R)-Baclofen hydrochloride
GABA Receptor Agonist
(R)-Baclofen hydrochloride is a selective agonist of the GABAB receptor. This compound is primarily utilized for its muscle relaxant properties and has been studied for its potential therapeutic effects in conditions such as spasticity and pain management. Its mechanism of action involves the modulation of neurotransmitter release, thereby influencing synaptic transmission and muscle tone. Research applications include neuroscience studies and investigations into GABAB receptor pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 63701-55-3 |
| Applications | GABA Receptor Agonist |
| Formula | C10H13Cl2NO2 |
| Molecular Weight | 250.12 |
| Synonyms | Arbaclofen hydrochloride; STX 209 hydrochloride |
| SMILES | ClC1=CC=C([C@](CC(O)=O)([H])CN)C=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.