Fig. 1 · Structure
Documents & Downloads
(R)-BAY-85-8501
BAY-85-8501 Enantiomer
(R)-BAY-85-8501 is the less active enantiomer of BAY-85-8501, a selective and potent inhibitor of Human Neutrophil Elastase (HNE) with an IC50 of 65 pM. This compound is utilized in research to investigate the role of HNE in various inflammatory conditions and to explore therapeutic strategies targeting this enzyme. Its specific inhibitory action makes it a valuable tool for studying neutrophil function and related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2446175-39-7 |
| Applications | BAY-85-8501 Enantiomer |
| Formula | C22H17F3N4O3S |
| Molecular Weight | 474.46 |
| SMILES | N#CC1=C(C)N(C2=CC=CC(C(F)(F)F)=C2)C(N(C)[C@H]1C3=CC=C(C#N)C=C3S(=O)(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.