(R)-Desamino lenalidomide-5-Br is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein in cellular contexts. This compound can be utilized in the design of PROTACs (proteolysis targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its unique mechanism allows for targeted protein degradation, making it valuable for research applications in drug discovery and therapeutic development.
(R)-Desamino lenalidomide-5-Br is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein in cellular contexts. This compound can be utilized in the design of PROTACs (proteolysis targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its unique mechanism allows for targeted protein degradation, making it valuable for research applications in drug discovery and therapeutic development.
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