(R)-DM4-SPDP

Catalog No.: A41596
Antibody-drug Conjugates
(R)-DM4-SPDP is a conjugate consisting of the linker SPDP and the cytotoxic agent DM4, specifically designed for the development of antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of therapeutic agents to tumor cells, enhancing the efficacy of cancer treatment while minimizing systemic toxicity. (R)-DM4-SPDP is ideal for research applications focused on ADC design and optimization in oncology studies.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(R)-DM4-SPDP is a conjugate consisting of the linker SPDP and the cytotoxic agent DM4, specifically designed for the development of antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of therapeutic agents to tumor cells, enhancing the efficacy of cancer treatment while minimizing systemic toxicity. (R)-DM4-SPDP is ideal for research applications focused on ADC design and optimization in oncology studies.
Product Information
Catalog NumA41596
FormulaC45H61ClN4O14S2
Molecular Weight981.57
CAS Number2245698-48-8
SMILESC[C@]1([C@H](CC(N(C(C=C(C2)C=C3OC)=C3Cl)C)=O)OC([C@@H](C)N(C)C(CCC(C)(C)SSCCC(ON(C4=O)C(CC4)=O)=O)=O)=O)[C@@]([C@@H]([C@](OC5=O)([H])C[C@]([C@@H](/C=C/C=C2\C)OC)(N5)O)C)([H])O1
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