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(R)-ELX-02

(R)-ELX-02, also known as NB-124, is an eukaryotic ribosomal selective glycoside (ERSG) designed to promote read-through activity in cells harboring nonsense mutations. By enhancing the synthesis of full-length functional proteins, (R)-ELX-02 holds potential for therapeutic applications in genetic disorders resulting from premature termination codons. This compound serves as a valuable tool for researchers investigating treatments for diseases linked to protein synthesis defects.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1375073-95-2
Formula	C₁₉H₃₈N₄O₁₀
Molecular Weight	482.53
SMILES	C[C@H]([C@@]([H])(O[C@@H]1O[C@@H]([C@@H]2O[C@@H]3O[C@]([H])([C@@H](C)N)[C@@H](O)[C@H]3O)[C@@H](N)C[C@@H](N)[C@@H]2O)[C@@H](O)[C@H](O)[C@H]1N)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.