Fig. 1 · Structure
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(R)-Exatecan Intermediate 1
Camptothecin Intermediate
(R)-Exatecan Intermediate 1 is a crucial intermediate in the synthesis of Camptothecin derivatives. It serves as a building block for the preparation of Exatecan mesylate (DX8951f), a compound noted for its low sensitivity to multidrug resistance. This characteristic enhances its potential effectiveness in anti-tumor research, making (R)-Exatecan Intermediate 1 a valuable reagent for investigations aimed at cancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 110351-91-2 |
| Applications | Camptothecin Intermediate |
| Formula | C13H13NO5 |
| Molecular Weight | 263.25 |
| SMILES | O=C1[C@@](O)(CC)C(C=C23)=C(CO1)C(N3CCC2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.