Fig. 1 · Structure

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(R)-(-)-Felodipine-d5

Stable Isotope

(R)-(-)-Felodipine-d5 is a deuterium-labeled analogue of the S enantiomer of Felodipine, a potent vasoselective calcium channel antagonist. This compound effectively lowers blood pressure through its selective action on vascular smooth muscle, particularly in resistance vessels. In addition to its antihypertensive properties, Felodipine has been shown to induce autophagy and is capable of crossing the blood-brain barrier. It is suitable for research applications involving pharmacokinetics and metabolic studies of calcium channel blockers.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1217744-87-0
Applications Stable Isotope
Formula C18H14D5Cl2NO4
Molecular Weight 389.28
SMILES
[2H]C([2H])([2H])C([2H])([2H])OC(C1=C(C)NC(C)=C(C(OC)=O)[C@@]1([H])C2=C(C(Cl)=CC=C2)Cl)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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