Fig. 1 · Structure
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(R)-FTY720-vinylphosphonate
SK1 Inhibitor
(R)-FTY720-vinylphosphonate is a selective inhibitor of sphingosine kinase 1 (SK1), which plays a crucial role in sphingolipid metabolism. This compound functions as an analog of FTY720 and has potential applications in the study of solid tumors, including breast cancer. Its effectiveness in modulating SK1 activity makes it valuable for exploring therapeutic strategies targeting sphingosine signaling pathways in oncology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1142015-25-5 |
| Applications | SK1 Inhibitor |
| Formula | C20H34NO4P |
| Molecular Weight | 383.46 |
| SMILES | O=P(O)(O)/C=C/[C@](CO)(N)CCC1=CC=C(C=C1)CCCCCCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.