Fig. 1 · Structure
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(R)-Levrazoxane
Optical Isomer of Dexrazoxane
(R)-Levrazoxane is an optical isomer of Dexrazoxane that targets dihydropyrimidine amidohydrolase (DPHase) for enzymatic hydrolysis, producing one-ring open intermediates. This compound demonstrates enhanced radiosensitization effects in EMT6 mouse mammary tumor cells compared to its counterpart, Dexrazoxane. Its potential applications extend to the study of liver and kidney-related diseases, highlighting its importance in cancer research and therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 24613-06-7 |
| Applications | Optical Isomer of Dexrazoxane |
| Formula | C11H16N4O4 |
| Molecular Weight | 268.27 |
| Synonyms | (R)-ICRF 186 |
| SMILES | C[C@H](CN(CC(N1)=O)CC1=O)N(CC(N2)=O)CC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.