Fig. 1 · Structure
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(R)-Lisofylline
Lysophosphatidic Acid Acyltransferase Inhibitor
(R)-Lisofylline is a potent lysophosphatidic acid acyltransferase inhibitor, exhibiting an IC50 of 0.6 μM. This compound possesses anti-inflammatory properties and disrupts IL-12 signaling-mediated STAT4 activation. It is particularly relevant for research in type 1 diabetes and autoimmune disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 100324-81-0 |
| Applications | Lysophosphatidic Acid Acyltransferase Inhibitor |
| Formula | C13H20N4O3 |
| Molecular Weight | 280.32 |
| Synonyms | (R)-Lisophylline |
| SMILES | O=C(N1CCCC[C@H](O)C)N(C)C2=C(N(C)C=N2)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.