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Other Forms

Form	MW
(R)-LY-41 This page	273.41
(S)-LY-41	273.41

(R)-LY-41

5-HT1A Receptor Agonist

(R)-LY-41 is a selective agonist of the 5-HT1A receptor. It is known to effectively reduce the accumulation of 5-hydroxytryptophan in the rat brain induced by decarboxylase inhibitors, thereby influencing serotonin synthesis. This compound can also lower body temperature in rats and inhibit escape responses, contributing to the induction of the 5-HT behavioral syndrome, albeit with less potency compared to its S-enantiomer. (R)-LY-41 is an important reagent for research into neurological disorders, particularly depression and anxiety.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	136296-43-0
Applications	5-HT1A Receptor Agonist
Formula	C₁₈H₂₇NO
Molecular Weight	273.41
SMILES	CC(C1=CC=CC2=C1C[C@H](N(CCC)CCC)CC2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.