Fig. 1 · Structure
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(R)-Omeprazole sodium
Cytochrome P450 Inhibitor
(R)-Omeprazole sodium is a cytochrome P450 inhibitor primarily targeting CYP2C19. This compound effectively inhibits gastric acid secretion and demonstrates reversible direct and metabolism-dependent inhibition of metabolic pathways influenced by cytochrome P450 enzymes. (R)-Omeprazole sodium's pharmacokinetics can be modified by interactions with excipients such as mannitol, potentially affecting its bioavailability in various formulations. Its applications include studies on gastric acid regulation and drug metabolism in pharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 161796-77-6 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C17H18N3NaO3S |
| Molecular Weight | 367.40 |
| SMILES | O=[S@@](C1=NC2=CC=C(OC)C=C2N1[Na])CC3=NC=C(C)C(OC)=C3C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.